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Comment le CBD et le THC affectent-ils l’activité des cellules microgliales dans les maladies neurodégénératives, notamment dans les maladies d’Alzheimer et de Parkinson ?

Comment le CBD et le THC affectent-ils l’activité des cellules microgliales dans les maladies neurodégénératives, notamment dans les maladies d’Alzheimer et de Parkinson ? Le CBD et le THC réduisent la neuroinflammation en modulant l’activité des cellules microgliales, les cellules immunitaires du cerveau. Le CBD supprime la libération de cytokines pro-inflammatoires et favorise le passage à un état microglial anti-inflammatoire, tandis que l’interaction du THC avec les récepteurs CB2 atténue davantage l’activation microgliale. Cette double action protège les neurones des dommages oxydatifs et du stress inflammatoire, ralentissant ainsi la progression des maladies neurodégénératives comme la maladie d’Alzheimer et la maladie de Parkinson. Ensemble, ils favorisent un environnement neuroprotecteur en réduisant la suractivation microgliale chronique. Cette synergie soutient de meilleurs résultats dans ces maladies.
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