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Kako razvoj tolerancije utječe na psihoaktivne učinke kanabinoida tijekom vremena?

Kako razvoj tolerancije utječe na psihoaktivne učinke kanabinoida tijekom vremena? Ponovljenom upotrebom psihoaktivnih kanabinoida razvija se tolerancija jer CB1 receptori postaju smanjeno regulirani i manje osjetljivi na THC. To znači da će s vremenom možda biti potrebne veće doze THC-a za postizanje iste razine psihoaktivnosti. Tolerancija također utječe na učinak okruženja, budući da prisutnost drugih kanabinoida ili terpena možda više neće imati isti utjecaj na učinke THC-a. Kod nekih pojedinaca može se pojaviti unakrsna tolerancija s drugim kanabinoidima ili čak sintetskim kanabinoidima, što zahtijeva pažljivije upravljanje konzumacijom kanabinoida. Tolerancija također može utjecati na dugoročne terapijske rezultate, čineći liječenje kanabinoidima manje učinkovitim osim ako se ne prilagode doze.

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IMPORTANT: This information is NOT MEDICAL ADVICE and is only provided for general informational purposes only. Always first seek the advice of your doctor or a healthcare professional first before taking a CBD product or vitamin supplement if you are unsure. Statements regarding dietary supplements have not been evaluated by the FDA and are not intended to diagnose, treat, cure, or prevent any disease or health condition. No claims are intended to be made about the functions or ability of a CBD infused cosmetic product and/ or vitamin supplement to provide any specific health or wellness benefits. None of our CBD strips, patches or other CBD products are described, promoted or marketed as having any function not listed in the COSING Information Database. Any information provided here about CBD or any other ingredient and/ or product is strictly for general informational purposes and should not be interpreted as medical, therapeutic, or diagnostic advice. CBD products are not intended to diagnose, treat, cure, or prevent any disease or health condition. You are advised to always first consult with a doctor or a qualified healthcare professional before using any CBD product, particularly if you any of the following apply. DO NOT USE CBD IF PREGANT, BREAST FEEDING OR IF YOU HAVE A SERIOUS MEDICAL CONDITION. DO NOT USE IF PACKAGING HAS BEEN OPENED DURING SHIPPING. DISCONTINUE USE IF ANY ADVERSE REACTION OR SYMPTOM OCCURS. CONTACT A DOCTOR IF REACTION OR SYMPTOM CONTINUES. FOR ADULTS ONLY. STORE OUT OF REACH OF CHILDREN.