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Hur påverkar CBGA modulering av endocannabinoidsystemet jämfört med CBD?

Hur påverkar CBGA modulering av endocannabinoidsystemet jämfört med CBD? CBGA påverkar det endocannabinoida systemet främst genom att interagera med CB1- och CB2-receptorer, men det modulerar också andra signalvägar. Till skillnad från CBD, som indirekt modulerar dessa receptorer genom att påverka endocannabinoidåterupptag och nedbrytning, interagerar CBGA direkt med cannabinoidreceptorer, fastän med lägre bindningsaffinitet. Dessutom har CBGA visat sig aktivera peroxisomproliferatoraktiverade receptorer (PPAR), vilket kan ge en unik effekt jämfört med CBD:s mer indirekta effekter på endocannabinoidsystemet.

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