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¿Cómo influyen el CBD y el THC en el proceso de neurogénesis en el hipocampo en pacientes con depresión o trastorno de estrés postraumático? El CBD y el THC promueven la neurogénesis activando los receptores CB1 y CB2 y reduciendo la neuroinflamación en el hipocampo. El THC estimula directamente la señalización endocannabinoide, mejorando el crecimiento de nuevas neuronas, mientras que el CBD apoya este proceso al reducir el estrés oxidativo y aumentar la actividad del receptor de serotonina. Juntos, mejoran la regulación del estado de ánimo y la función cognitiva en pacientes con depresión y trastorno de estrés postraumático. Esta sinergia restaura la plasticidad del hipocampo y reduce síntomas como la ansiedad y la desregulación emocional. Los efectos combinados proporcionan un enfoque holístico para el tratamiento de salud mental.
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