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¿Cómo influyen el CBD y el THC en la permeabilidad de la barrera hematoencefálica y sus efectos en enfermedades neurodegenerativas como la ELA? El CBD y el THC reducen la disfunción de la barrera hematoencefálica (BHE) al reducir la inflamación y el estrés oxidativo. El THC activa los receptores CB1 para estabilizar la señalización neuronal, mientras que las propiedades antioxidantes del CBD protegen las células endoteliales que recubren la BHE. Juntos, mejoran la integridad de la barrera, permitiendo la entrada selectiva de compuestos terapéuticos al tiempo que reducen la infiltración neurotóxica. Esta interacción frena la progresión de la ELA y otras enfermedades neurodegenerativas. Su sinergia apoya los procesos protectores y reparadores en el cerebro.
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