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How does the molecular structure of cannabinoids affect their stability in transdermal patches over time?

How does the molecular structure of cannabinoids affect their stability in transdermal patches over time? The molecular structure of cannabinoids affects their stability by determining their susceptibility to oxidation, light degradation, and interaction with other components in the patch. Cannabinoids with more reactive double bonds, like THC, may degrade faster compared to more stable molecules like CBD. The patch formulation can include antioxidants or stabilizing agents to prevent cannabinoid degradation over time. Furthermore, the encapsulation of cannabinoids in protective delivery systems like liposomes or microparticles can help maintain their stability.

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