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Hvordan påvirker typen af hud (f.eks. tynd versus tyk) på applikationsstedet cannabinoidabsorption fra plastre?

Hvordan påvirker typen af ​​hud (f.eks. tynd versus tyk) på applikationsstedet cannabinoidabsorption fra plastre? Tykkelsen og sammensætningen af ​​huden på applikationsstedet påvirker direkte absorptionshastigheden af ​​cannabinoider. Tyndere hud, såsom omkring håndleddene eller de indre arme, giver mulighed for lettere penetrering, hvilket fører til hurtigere absorption. Tykkere hud, som på håndflader eller såler, fungerer som en mere væsentlig barriere, der kræver højere cannabinoidkoncentrationer eller forbedrede leveringssystemer. Områder med flere talgkirtler kan lette cannabinoidabsorption på grund af det øgede lipidindhold i disse regioner.

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