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Kakav je učinak THC-a na neurogenezu u hipokampusu?

Kakav je učinak THC-a na neurogenezu u hipokampusu? Pokazalo se da THC smanjuje neurogenezu u hipokampusu, osobito kod kronične uporabe. Dok akutna izloženost THC-u može imati prolazne učinke na neuroplastičnost, dugotrajna uporaba može oslabiti rađanje novih neurona, potencijalno utječući na procese učenja i pamćenja. Međutim, CBD je pokazao suprotan učinak, potičući neurogenezu u hipokampusu, što može pomoći u ublažavanju nekih kognitivnih oštećenja THC-a. Utjecaj THC-a na neurogenezu povezan je s njegovom modulacijom CB1 receptora, gdje kronična stimulacija može ometati stvaranje i održavanje novih moždanih stanica. Ovi učinci naglašavaju važnost umjerenosti u uporabi THC-a, posebno za održavanje kognitivnog zdravlja.

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