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Kako endokanabinoidni sustav regulira upalu kod autoimunih bolesti?

Kako endokanabinoidni sustav regulira upalu kod autoimunih bolesti? Endokanabinoidni sustav regulira upalu kod autoimunih bolesti kroz interakciju s CB2 receptorima u imunološkom sustavu. Kada se aktiviraju, CB2 receptori pomažu modulirati aktivnost imunoloških stanica, smanjujući proizvodnju proupalnih citokina i potičući protuupalne reakcije. Ova regulacija pomaže uravnotežiti funkciju imunološkog sustava, sprječavajući pretjerane imunološke reakcije koje mogu oštetiti tkiva, kao što se vidi kod autoimunih bolesti poput reumatoidnog artritisa i lupusa. ECS također radi na održavanju imunološke homeostaze, sprječavajući pretjeranu upalu. Podržavajući funkciju ECS-a, CBD može doprinijeti smanjenju upale u autoimunim stanjima.
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