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Kako kanabinoidi utječu na neurogenezu i njezinu ulogu u modulaciji psihoaktivnih iskustava?

Kako kanabinoidi utječu na neurogenezu i njezinu ulogu u modulaciji psihoaktivnih iskustava? Kanabinoidi, posebice THC i CBD, dokazano utječu na neurogenezu ili stvaranje novih neurona u regijama poput hipokampusa. Utvrđeno je da THC potiče neurogenezu pod određenim uvjetima, ali njegovi psihoaktivni učinci mogu ometati učenje i pamćenje, što su procesi povezani s neurogenezom. S druge strane, čini se da CBD ima neuroprotektivne učinke i može podržati neurogenezu na način koji je koristan za kognitivnu funkciju i cjelokupno mentalno zdravlje. Modulacija neurogeneze igra značajnu ulogu u tome kako kanabinoidi utječu na dugoročnu funkciju mozga i mogu utjecati na psihoaktivnost mijenjanjem sposobnosti mozga da se prilagodi podražajima iz okoline. Stoga utjecaj kanabinoida na neurogenezu može pojačati i ograničiti njihove psihoaktivne učinke, ovisno o kontekstu.

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