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Koje su implikacije THC-a u modulaciji komunikacije osovine mikrobioma, crijeva i mozga?

Koje su implikacije THC-a u modulaciji komunikacije osovine mikrobioma, crijeva i mozga? THC može utjecati na osovinu mikrobiom-crijeva-mozak mijenjanjem sastava crijevne mikrobiote, što može utjecati na cjelokupnu imunološku funkciju i zdravlje mozga. Istraživanje je pokazalo da djelovanje THC-a na CB2 receptore u crijevima može modulirati upalu crijeva i crijevnu propusnost, što može utjecati na živčani sustav putem živca vagusa. Utječući na mikrobiom crijeva, THC potencijalno može promijeniti raspoloženje i kognitivnu funkciju putem mikrobnih metabolita koji utječu na proizvodnju neurotransmitera i imunološke reakcije. Ovi učinci upućuju na to da THC može igrati ulogu u modulaciji komunikacije crijeva i mozga, nudeći nove uvide u psihijatrijske poremećaje i neurološko zdravlje. Međutim, potrebno je više istraživanja kako bi se u potpunosti razumjele implikacije ovih interakcija.

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