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Quali sono i vantaggi dell’utilizzo di trasportatori idrofili rispetto a quelli lipofili nei cerotti transdermici con cannabinoidi?

Quali sono i vantaggi dell’utilizzo di trasportatori idrofili rispetto a quelli lipofili nei cerotti transdermici con cannabinoidi? I trasportatori idrofili, che attraggono l’acqua, possono aiutare a trasportare efficacemente i cannabinoidi idrofili attraverso la pelle formando soluzioni a base acquosa che migliorano la penetrazione. I trasportatori lipofili, d'altro canto, sono ideali per i cannabinoidi lipofili come CBD, CBG e CBN, promuovendone un migliore assorbimento sfruttando l'ambiente lipidico naturale della pelle. L’utilizzo di una combinazione di entrambi i tipi di trasportatori in un cerotto transdermico può fornire un profilo di rilascio bilanciato per cannabinoidi con varie proprietà di solubilità, migliorando sia l’assorbimento che gli effetti terapeutici. La scelta del carrier influenza anche la velocità di rilascio, garantendo che il cerotto soddisfi le esigenze terapeutiche previste.

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