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Quelles sont les propriétés pharmacologiques uniques du CBN par rapport à d'autres cannabinoïdes comme le THC et le CBD ? Le CBN, ou cannabinol, est un cannabinoïde aux propriétés pharmacologiques uniques, principalement dues à ses légers effets psychoactifs et à ses propriétés sédatives potentielles. Contrairement au THC, puissant agoniste des récepteurs CB1, le CBN a une affinité plus faible pour ces récepteurs et peut avoir des effets sédatifs sans provoquer de psychoactivité significative. De plus, le CBN renforcerait les effets d'autres cannabinoïdes, notamment en favorisant le sommeil. En revanche, le CBD est non psychoactif et agit principalement comme antagoniste des récepteurs CB1. Les propriétés distinctes du CBN suggèrent son potentiel pour les troubles du sommeil et comme composant synergique dans les formulations de cannabinoïdes (Stark et al., 2020).
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