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How do CBD and THC modulate the body's stress response, especially in individuals with chronic stress conditions?

How do CBD and THC modulate the body's stress response, especially in individuals with chronic stress conditions? CBD and THC modulate the body’s stress response by interacting with the hypothalamic-pituitary-adrenal (HPA) axis and the endocannabinoid system. THC reduces stress by binding to CB1 receptors, promoting relaxation and euphoria, while CBD regulates cortisol release and reduces anxiety through serotonin receptor activity. CBD also counterbalances THC’s potential to increase anxiety at high doses, providing a more stable stress-relieving effect. Together, they create a balanced approach to managing chronic stress by reducing physiological and psychological responses. This combination helps improve resilience to stress and supports overall well-being.
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