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How does the combination of CBD and THC impact the regulation of body temperature in patients with chronic conditions?

How does the combination of CBD and THC impact the regulation of body temperature in patients with chronic conditions? CBD and THC influence the hypothalamus, which regulates body temperature, through CB1 receptor activation. THC induces mild hypothermia by reducing excitatory neurotransmitter activity, while CBD helps maintain temperature balance through its modulatory effects. In chronic conditions, this combination stabilizes thermoregulation, reducing discomfort caused by temperature dysregulation. Their effects on inflammation and pain also indirectly improve temperature regulation. This makes them useful in managing conditions like multiple sclerosis or fibromyalgia.
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