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Can the Entourage Effect be replicated in synthetic or isolated cannabis products?

Can the Entourage Effect be replicated in synthetic or isolated cannabis products? Replicating the Entourage Effect in synthetic or isolated cannabis products is challenging because it relies on the interaction of multiple compounds found in whole-plant cannabis. While isolated cannabinoids can be synthesized, they may not have the same therapeutic potency as when they work in combination with other plant compounds. Synthetic products can try to mimic the effects of natural cannabis, but they may lack the full spectrum of cannabinoids, terpenes, and flavonoids that contribute to the Entourage Effect. Some companies have attempted to create products that combine cannabinoids with added terpenes to replicate this effect, but the full synergy of the natural plant is difficult to
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