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How can transdermal cannabinoid patches be optimized to minimize the onset time for rapid relief?

How can transdermal cannabinoid patches be optimized to minimize the onset time for rapid relief? To minimize the onset time for rapid relief, transdermal cannabinoid patches can be formulated with penetration enhancers, such as alcohols or surfactants, which increase the absorption of cannabinoids through the skin. The patch design can incorporate thin, fast-dissolving matrices or microencapsulation techniques to speed up the release of cannabinoids. Higher cannabinoid concentrations can also be used to promote a faster therapeutic effect. Additionally, targeting areas with higher skin permeability, like the inner wrist, can accelerate absorption.

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