What are the potential risks associated with high-dose cannabinoid use in clinical settings?
What are the potential risks associated with high-dose cannabinoid use in clinical settings? High-dose cannabinoid use in clinical settings can lead to several potential risks, including increased side effects such as anxiety, paranoia, and cognitive impairment. Patients may experience dose-dependent adverse effects like dizziness, sedation, and altered motor function, which could complicate treatment adherence and safety. Additionally, high doses of cannabinoids can result in tolerance and withdrawal symptoms, affecting long-term efficacy and patient outcomes. Monitoring and dose adjustment are crucial to mitigate these risks and ensure patient safety during cannabinoid therapy. Ongoing research is needed to establish optimal dosing guidelines to balance efficacy and safety in clinical practice (Wang et al., 2021).