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What are the safety concerns associated with using cannabinoid transdermal patches, particularly regarding systemic absorption?

What are the safety concerns associated with using cannabinoid transdermal patches, particularly regarding systemic absorption? The primary safety concern with cannabinoid transdermal patches is the potential for excessive systemic absorption, which could lead to unwanted side effects such as dizziness, fatigue, or impaired cognitive function. Over-absorption can occur if the patch is too large or if the release mechanism is not controlled properly. Careful calibration of dosage, along with patch size and formulation, ensures that cannabinoids are delivered at the correct rate. Regular monitoring and testing for safety help mitigate these risks.

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