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Hoe moduleren CBD en THC de circadiane genexpressie in de hersenen en de lever, en welke impact heeft dit op de slaap-waakcycli? CBD en THC beïnvloeden het circadiane ritme door interactie met cannabinoïdereceptoren in hersengebieden zoals de suprachiasmatische kern. THC bevordert het begin van de slaap door CB1-receptoren te activeren, terwijl CBD de waakzaamheid verbetert en de circadiaanse genexpressie in de lever reguleert. Deze combinatie helpt verstoorde slaap-waakcycli te herstellen bij aandoeningen zoals slapeloosheid. De effecten van CBD op serotoninereceptoren verbeteren ook de slaapkwaliteit. Samen bieden ze een evenwichtige benadering van circadiane regulatie.
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