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Kako THC utječe na funkciju mitohondrija u neuronima?

Kako THC utječe na funkciju mitohondrija u neuronima? THC utječe na funkciju mitohondrija u neuronima utječući na proizvodnju energije, oksidativni stres i preživljavanje stanica. THC može oslabiti mitohondrijsko disanje, što dovodi do povećanja reaktivnih kisikovih vrsta (ROS) i oksidativnog oštećenja, što može doprinijeti neurodegeneraciji. Osim toga, pokazalo se da THC mijenja dinamiku mitohondrija, uključujući procese fisije i fuzije, koji su ključni za održavanje zdrave mitohondrijske funkcije. Dok neke studije sugeriraju da neuroprotektivni učinci THC-a mogu ublažiti ove izazove, kronična izloženost ipak može rezultirati mitohondrijskom disfunkcijom, osobito u područjima poput hipokampusa i prefrontalnog korteksa. Ovi poremećaji mogu pridonijeti kognitivnom padu i povećanju neuroinflamacije tijekom vremena.

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