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In che modo i cannabinoidi contenuti nei cerotti transdermici interagiscono con il microbioma della pelle, se non lo fanno?

In che modo i cannabinoidi contenuti nei cerotti transdermici interagiscono con il microbioma della pelle, se non lo fanno? I cannabinoidi possono modulare le popolazioni microbiche esercitando proprietà antibatteriche e antifungine, in particolare contro i ceppi patogeni. Il microbioma cutaneo può anche influenzare il metabolismo dei cannabinoidi, alterandone potenzialmente la biodisponibilità e l’efficacia. Le formulazioni di cerotti che includono prebiotici o agenti antimicrobici possono aiutare a mantenere un microbioma equilibrato. Sono necessarie ulteriori ricerche per comprendere appieno l’interazione tra cannabinoidi e comunità microbiche della pelle (Freeman et al., 2019).

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