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Kāda loma aknu glikuronizācijas un sulfonēšanas procesiem ir CBD un citu nepsihoaktīvo kaņepju savienojumu metabolismā?

Kāda loma aknu glikuronizācijas un sulfonēšanas procesiem ir CBD un citu nepsihoaktīvo kaņepju savienojumu metabolismā? Glikuronizācija un sulfonēšana ir II fāzes detoksikācijas procesi, kas ietver glikuronskābes vai sulfātu grupu pievienošanu CBD un citiem nepsihoaktīviem kaņepju savienojumiem, padarot tos ūdenī šķīstošākus izvadīšanai. Šie procesi notiek aknās un palīdz efektīvāk izvadīt kanabinoīdus no organisma. Glikuronizācija ir īpaši nozīmīga CBD metabolismā, izraisot metabolītu veidošanos, kas tiek izvadīti ar urīnu. Sulfonēšana arī veicina kanabinoīdu metabolismu, bet mazākā mērā. Kopā šie ceļi palīdz regulēt CBD iedarbības ilgumu un intensitāti organismā.

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