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What is the impact of different skin types on the absorption and effectiveness of cannabinoids from transdermal patches?

What is the impact of different skin types on the absorption and effectiveness of cannabinoids from transdermal patches? Oily skin can enhance cannabinoid absorption by improving solubility, while dry skin may act as a barrier, reducing penetration. Thicker skin, such as on the palms or soles, slows absorption, whereas thinner skin, like behind the ears, allows for faster diffusion. Individual differences in skin pH, hydration, and lipid content also influence how well cannabinoids penetrate. Formulations should account for these variations to ensure consistent effectiveness across diverse skin types.

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