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Hoe beïnvloeden cannabinoïden in transdermale pleisters de bloedsomloop en de afgifte van voedingsstoffen of andere medicijnen aan de huid?

Hoe beïnvloeden cannabinoïden in transdermale pleisters de bloedsomloop en de afgifte van voedingsstoffen of andere medicijnen aan de huid? Cannabinoïden beïnvloeden de lokale vasodilatatie, waardoor de afgifte van voedingsstoffen en zuurstof aan de huidweefsels kan worden verbeterd. Een verhoogde bloedstroom kan de transdermale absorptie verbeteren, maar kan ook de distributie van gelijktijdig toegediende medicijnen veranderen. Interactie met bloedvaten in de huid kan helpen bij het moduleren van ontstekings- en huidherstelprocessen. Een zorgvuldige formulering is nodig om onbedoelde geneesmiddelinteracties te voorkomen bij gebruik van cannabinoïdepleisters in combinatie met andere plaatselijke behandelingen (Giacoppo et al., 2014).

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