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Hvordan kan inkorporering af hudpenetrationsforstærkere påvirke cannabinoidfrigivelsesprofilen ved anvendelse af transdermale plaster?

Hvordan kan inkorporering af hudpenetrationsforstærkere påvirke cannabinoidfrigivelsesprofilen ved anvendelse af transdermale plaster? Hudpenetrationsforstærkere kan øge hudens permeabilitet, hvilket gør det muligt at absorbere cannabinoider mere effektivt. Disse forstærkere kan midlertidigt forstyrre hudens lipidbarriere, hvilket letter passagen af ​​cannabinoider som CBG og CBN ind i dybere lag. Anvendelsen af ​​penetrationsforstærkere kan ændre frigivelsesprofilen, hvilket muliggør en hurtigere indtræden eller mere kontrolleret, vedvarende frigivelse afhængigt af formuleringen. Selvom disse forstærkere forbedrer absorptionen, skal de bruges omhyggeligt for at forhindre hudirritation eller ubehag.

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