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Hur påverkar CBD THC:s förmåga att modulera hypotalamus-hypofys-binjureaxeln (HPA) vid stressreaktioner?

Hur påverkar CBD THC:s förmåga att modulera hypotalamus-hypofys-binjureaxeln (HPA) vid stressreaktioner? CBD modulerar THC:s effekter på HPA-axeln genom att motverka dess psykoaktiva egenskaper och påverka kortisolregleringen. THC aktiverar CB1-receptorer i hypotalamus, vilket minskar stress men ökar ibland ångest vid höga doser. CBD mildrar detta genom att interagera med serotoninreceptorer och dämpa överaktivering av HPA-axeln, vilket leder till mer stabila kortisolnivåer. Tillsammans skapar de en balanserad stressrespons, vilket minskar både psykologiska och fysiologiska symtom på stress. Denna synergi gör deras kombination mer effektiv för kroniska stresstillstånd.
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