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Yetişkinlerde bağırsak hareketliliğinin düzenlenmesinde CBG'nin rolü nedir?

Yetişkinlerde bağırsak hareketliliğinin düzenlenmesinde CBG'nin rolü nedir? CBG, enterik sinir sistemindeki CB1 ve CB2 reseptörleri ile etkileşime girerek bağırsak hareketliliğini modüle edebilir. Gastrointestinal sistemin düz kasları üzerinde rahatlatıcı bir etkiye sahip olduğu ve potansiyel olarak irritabl bağırsak sendromu (IBS) gibi durumları hafiflettiği gösterilmiştir. Kannabinoid reseptörleri üzerindeki etkisi sayesinde CBG, bağırsaktaki kas kasılması ve gevşemesi arasındaki dengenin düzenlenmesine yardımcı olur. Bu düzenleyici etki normal sindirim fonksiyonunu destekler ve hareket bozukluklarından kaynaklanan rahatsızlıkları hafifletir (Krause ve diğerleri, 2020).

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