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Hvordan kan cannabinoid-infunderede plastre designes til at sikre ensartet dosering gennem hele påføringsperioden, hvilket forhindrer dosisvariabilitet?

Hvordan kan cannabinoid-infunderede plastre designes til at sikre ensartet dosering gennem hele påføringsperioden, hvilket forhindrer dosisvariabilitet? For at sikre ensartet dosering kan cannabinoid-infunderede plastre designes med systemer med kontrolleret frigivelse, såsom matrix-baserede systemer eller mikroindkapsling, som frigiver cannabinoider støt over tid. Disse systemer forhindrer frigivelsesudbrud, der kan føre til dosisvariabilitet. Ensartet fordeling af cannabinoider i plastermaterialet sammen med omhyggelig kontrol over plasterets klæbende egenskaber sikrer yderligere ensartet dosering. Regelmæssig testning og kvalitetskontrol under fremstillingsprocessen sikrer, at hvert plaster leverer den tilsigtede dosis gennem hele påføringsperioden.

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