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Kako limonen i CBD utječu na intracelularnu signalizaciju kalcija u neuronskim stanicama?

Kako limonen i CBD utječu na intracelularnu signalizaciju kalcija u neuronskim stanicama? Limonen i CBD mogu utjecati na intracelularnu signalizaciju kalcija u neuronskim stanicama modulacijom aktivnosti receptora i staničnog toka iona. Pokazalo se da CBD utječe na homeostazu kalcija interakcijom s TRPV1 receptorima i drugim ionskim kanalima, potencijalno mijenjajući dotok kalcija u neurone. Limonen, svojim učinkom na serotonin i druge receptorske sustave, može neizravno utjecati na signalizaciju kalcija reguliranjem otpuštanja neurotransmitera i stanične ekscitabilnosti. Zajedno, ovi spojevi mogu pružiti uravnotežen pristup modulaciji neuronske aktivnosti, potencijalno utječući na stanja poput boli, tjeskobe i neurodegenerativnih bolesti. Sinergija između limonena i CBD-a mogla bi pomoći u održavanju stanične ravnoteže kalcija, što je ključno za zdravlje i funkciju neurona.

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