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In che modo il CBD e il THC interagiscono con il sistema endocannabinoide dell'organismo per regolare l'appetito e l'assunzione di cibo nei pazienti obesi?

In che modo CBD e THC interagiscono con il sistema endocannabinoide dell'organismo per regolare l'appetito e l'assunzione di cibo nei pazienti obesi? Il THC stimola l'appetito attivando i recettori CB1 nell'ipotalamo, aumentando il rilascio di grelina. Il CBD controbilancia questo effetto modulando i recettori CB2 e promuovendo l'imbrunimento dei grassi, contribuendo potenzialmente alla regolazione del peso. Insieme, influenzano il bilancio energetico regolando i segnali di fame e le vie metaboliche. Questa duplice azione offre potenziali strategie terapeutiche per la gestione dell'obesità. I ​​loro effetti dipendono dal dosaggio e dalle modalità di somministrazione.
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