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Miten CB1-reseptorien aktivaatio vaikuttaa aivoihin?

Miten CB1-reseptorien aktivaatio vaikuttaa aivoihin? CB1-reseptorien aktivaatiolla aivoissa on merkittävä rooli monien kannabinoidien, erityisesti THC:n, psykoaktiivisten vaikutusten välittämisessä. Kun kannabinoidit, kuten THC, sitoutuvat CB1-reseptoreihin, ne moduloivat välittäjäaineiden vapautumista aivojen keskeisillä alueilla, mikä vaikuttaa mielialaan, muistiin ja kognitioon. Tämä vuorovaikutus vaikuttaa alueisiin, jotka ovat vastuussa nautinnosta, motivaatiosta ja kivun havaitsemisesta, mikä edistää muuttuneita aistikokemuksia ja euforiaa. CB1-reseptorien aktivaatio on mukana myös ruokahalun ja motorisen toiminnan säätelyssä. Tämän seurauksena kannabinoidien aiheuttama näiden reseptorien aktivointi johtaa kannabiksen ominaisiin vaikutuksiin, mukaan lukien "korkea".

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