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Kako CBD ublažava disregulaciju homeostaze neurotransmitera izazvanu THC-om?

Kako CBD ublažava disregulaciju homeostaze neurotransmitera izazvanu THC-om? CBD pomaže ublažiti disregulaciju homeostaze neurotransmitera izazvanu THC-om kroz više mehanizama. THC, osobito u visokim dozama, može promijeniti oslobađanje neurotransmitera, uključujući dopamin, glutamat i GABA, potencijalno dovodeći do neuravnotežene signalizacije i psihoaktivnih učinaka. CBD, interakcijom s CB1 receptorima, serotoninskim receptorima i drugim sustavima neurotransmitera, pomaže normalizirati otpuštanje neurotransmitera i smanjiti ekscitotoksičnost. Dodatno, pokazalo se da CBD povećava razinu anandamida, promičući endokanabinoidnu signalizaciju koja može dodatno obnoviti homeostazu. Ovaj uravnotežujući učinak CBD-a pomaže u sprječavanju tjeskobe, paranoje i drugih negativnih učinaka THC-a dok podupire cjelokupnu regulaciju neurotransmitera.

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