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Come si comportano i cerotti ai cannabinoidi nella popolazione anziana, soprattutto in termini di assorbimento ed effetti collaterali?

Come si comportano i cerotti ai cannabinoidi nella popolazione anziana, soprattutto in termini di assorbimento ed effetti collaterali? La pelle che invecchia presenta una diminuzione del contenuto lipidico, che può alterare i tassi di assorbimento transdermico. Un metabolismo più lento negli individui anziani può portare a una circolazione prolungata dei cannabinoidi, richiedendo aggiustamenti della dose. La fragilità della pelle richiede adesivi delicati per prevenire l'irritazione. Sono necessari studi clinici per ottimizzare l’efficacia e la sicurezza dei cerotti per gli utilizzatori più anziani (Baswan et al., 2020).

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