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In che modo il THC influisce sulle cellule endoteliali vascolari e sul sistema cardiovascolare?

In che modo il THC influisce sulle cellule endoteliali vascolari e sul sistema cardiovascolare? Il THC interagisce con i recettori CB1 e CB2 sulle cellule endoteliali vascolari, il che può portare alla vasodilatazione e all'aumento del flusso sanguigno. Questo effetto può contribuire all’abbassamento della pressione sanguigna in alcuni individui. Tuttavia, gli effetti cardiovascolari del THC possono variare a seconda dell'individuo e del contesto, con alcuni consumatori che riscontrano un aumento della frequenza cardiaca e della pressione sanguigna, soprattutto con dosi elevate. Questi cambiamenti potrebbero essere collegati agli effetti simpaticomimetici del THC, che attivano il sistema nervoso simpatico. Nel corso del tempo, questi effetti cardiovascolari possono aumentare i rischi per gli individui con patologie cardiache preesistenti.

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