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Comment les endocannabinoïdes influencent-ils la perception de la douleur par le corps via le système endocannabinoïde ?

Comment les endocannabinoïdes influencent-ils la perception de la douleur par le système endocannabinoïde ? Les endocannabinoïdes influencent la perception de la douleur en interagissant avec les récepteurs CB1 et CB2 du système nerveux et du système immunitaire. En se liant à ces récepteurs, les endocannabinoïdes contribuent à réduire la transmission des signaux douloureux, procurant ainsi des effets analgésiques. Le SEC module également la libération de neurotransmetteurs impliqués dans la sensation de douleur, tels que le glutamate et la substance P, réduisant ainsi la sensation générale de douleur. De plus, les endocannabinoïdes contribuent à réguler l'inflammation, souvent source de douleur. Ensemble, ces mécanismes permettent à l'organisme de gérer et de soulager la douleur plus efficacement.
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