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Can the Entourage Effect affect the side effects of cannabis?

Can the Entourage Effect affect the side effects of cannabis? Yes, the Entourage Effect can influence the side effects of cannabis by moderating or enhancing the effects of cannabinoids. For example, CBD can mitigate the anxiety or paranoia that some people experience from THC, leading to a more balanced effect. Terpenes like limonene or myrcene can also help reduce the intensity of unwanted side effects by promoting relaxation or counteracting THC’s stimulating effects. The Entourage Effect helps balance the plant’s overall impact, making cannabis use more enjoyable and minimizing potential negative side effects. This synergy is one of the reasons why whole-plant cannabis is preferred over isolated cannabinoids.
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