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How can cannabinoid patches be adapted to provide both systemic and local effects simultaneously?

How can cannabinoid patches be adapted to provide both systemic and local effects simultaneously? To provide both systemic and local effects, cannabinoid patches can be designed with multi-layer systems or a dual-release mechanism. A patch could release cannabinoids directly to the skin’s surface for local effects, while also incorporating a controlled-release system that allows cannabinoids to penetrate deeper for systemic effects. The cannabinoid profile (e.g., CBD, CBG, CBN) can be tailored to target both types of receptors for enhanced therapeutic outcomes. Careful formulation ensures that the patch delivers the desired effects without compromising on either localized or systemic efficacy.

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