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Kuidas CBD ja terpeenid nagu mütseen mõjutavad hematoentsefaalbarjääri läbilaskvust ja kuidas see mõjutab nende farmakokineetikat?

Kuidas CBD ja terpeenid nagu mütseen mõjutavad hematoentsefaalbarjääri läbilaskvust ja kuidas see mõjutab nende farmakokineetikat? CBD ja terpeenid, nagu mütseen, suurendavad hematoentsefaalbarjääri (BBB) ​​läbilaskvust, võimaldades kannabinoide tõhusamalt ajju toimetada. Eelkõige võib mütseen suurendada BBB läbilaskvust, mõjutades rakumembraanide voolavust, muutes CBD läbimise lihtsamaks. See suurenenud läbilaskvus suurendab kannabinoidide farmakokineetikat, parandades nende efektiivsust neuroloogiliste seisundite, nagu epilepsia või ärevuse, ravimisel. Hõlbutades paremat kannabinoidi kohaletoimetamist ajju, mängivad need terpeenid võtmerolli CBD ravitoime optimeerimisel. Selle tulemusena saavad kannabinoidid kesknärvisüsteemis tõhusamalt oma mõju avaldada.

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