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How can cannabinoid concentrations in patches be adjusted to provide a gradual onset of effects versus rapid relief?

How can cannabinoid concentrations in patches be adjusted to provide a gradual onset of effects versus rapid relief? To provide a gradual onset of effects, cannabinoid concentrations in patches can be adjusted through the use of controlled-release systems, which release cannabinoids over an extended period. These systems, such as matrix or reservoir-based patches, allow for slow diffusion of cannabinoids, providing consistent therapeutic effects over time. For rapid relief, patches can be designed with higher cannabinoid concentrations and faster delivery systems, such as microreservoirs or thinner layers, which allow for quicker absorption. The choice between these formulations depends on the desired therapeutic outcome, whether it’s for continuous relief or immediate relief.

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