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How does the design of cannabinoid patches influence their effectiveness for chronic conditions requiring consistent dosing?

How does the design of cannabinoid patches influence their effectiveness for chronic conditions requiring consistent dosing? Controlled-release matrices help maintain steady cannabinoid plasma levels over prolonged periods. Adhesive strength and flexibility impact wearability, ensuring continuous drug delivery. Reservoir and matrix systems offer different release kinetics, affecting therapeutic duration. Optimizing formulation for long-term adhesion and controlled diffusion enhances efficacy in chronic pain management (Benson, 2005).

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