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Kako THC utječe na imunološki sustav i njegovu interakciju s CB2 receptorima?

Kako THC utječe na imunološki sustav i njegovu interakciju s CB2 receptorima? THC stupa u interakciju s CB2 receptorima koji se prvenstveno nalaze u imunološkim stanicama i može modulirati imunološki odgovor, što obično rezultira imunosupresivnim učincima. Aktivacija CB2 receptora putem THC-a povezana je sa smanjenjem upale i može ublažiti simptome kod autoimunih stanja poput multiple skleroze ili reumatoidnog artritisa. Djelovanje THC-a na CB2 receptore pomaže regulirati otpuštanje proupalnih citokina, što dovodi do ukupne imunološke modulacije. Dok ti učinci mogu biti korisni za stanja poput autoimunih bolesti, dugotrajna ili pretjerana upotreba THC-a mogla bi oslabiti sposobnost tijela da se bori protiv infekcija ili utjecati na druge imunološke odgovore. Ovaj aspekt čini utjecaj THC-a na imunološku funkciju obećavajućim i složenim.

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