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Hur påverkar CBDA transkriptionsaktiviteten av NRF2 i antioxidantvägar?

Hur påverkar CBDA transkriptionsaktiviteten av NRF2 i antioxidantvägar? CBDA kan påverka transkriptionsaktiviteten av NRF2 (Nuclear Factor Erythroid 2-related Factor 2), en nyckelregulator för antioxidantförsvarsvägar. NRF2 aktiverar uttrycket av gener involverade i cellulärt försvar mot oxidativ stress, inklusive de som kodar för antioxidantenzymer. Genom att modulera NRF2-aktivitet kan CBDA förbättra cellens förmåga att neutralisera reaktiva syrearter (ROS) och minska oxidativ skada. Denna mekanism tyder på att CBDA kan stödja redoxbalans och skydda mot oxidativ stress-inducerade sjukdomar. Dess roll i NRF2-aktivering understryker CBDA:s potential som antioxidant och antiinflammatoriskt medel.

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