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How does skin elasticity affect the absorption and release of cannabinoids when applied via transdermal patches?

How does skin elasticity affect the absorption and release of cannabinoids when applied via transdermal patches? Skin elasticity impacts the absorption and release of cannabinoids in transdermal patches by influencing how well the patch adheres and how evenly cannabinoids are delivered. In areas with higher skin elasticity, such as younger skin or more flexible regions like the inner arm, the patch can conform better to the skin's surface, promoting consistent absorption. In contrast, less elastic or aging skin may have difficulties in maintaining patch adhesion or efficient cannabinoid release. In these cases, modifying the patch's adhesive strength or incorporating additional skin-conditioning agents can improve both adhesion and absorption.

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