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Hvordan interagerer THC og CBD for at påvirke sammensætningen af tarmmikrobiom?

Hvordan interagerer THC og CBD for at påvirke sammensætningen af ​​tarmmikrobiom? THC og CBD kan påvirke tarmmikrobiomet gennem deres interaktioner med det endocannabinoide system og tarmassocierede immunceller. THC kan ved at aktivere CB1-receptorer i mave-tarmsystemet påvirke tarmens motilitet og potentielt forstyrre det mikrobielle miljø. CBD har på den anden side vist sig at modulere CB2-receptorer i tarmen, hvilket kan fremme en sund mikrobiel sammensætning og tarmhomeostase. Når de kombineres, kan THC og CBD udøve en balancerende effekt på mikrobiomet, hvor CBD potentielt afbøder de forstyrrende virkninger af THC på tarmsundheden. Denne interaktion er vigtig for at forstå de potentielle tarm-hjerneakse-implikationer af cannabisbrug, især under tilstande som IBS eller Crohns sygdom.

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