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Hvordan kan flerlags depotplastre designes til at frigive cannabinoider med forskellige hastigheder over tid?

Hvordan kan flerlags depotplastre designes til at frigive cannabinoider med forskellige hastigheder over tid? Flerlags depotplastre kan designes med forskellige cannabinoidholdige lag, der opløser eller frigiver cannabinoider med varierende hastighed. Lagene kan formuleres med forskellige excipienser, såsom lipofile eller hydrofile bærere, for at skabe differentielle frigivelsesprofiler. Nogle lag kan frigive cannabinoider med det samme for hurtig lindring, mens andre frigives langsommere for længerevarende terapeutiske virkninger. Dette design kan optimeres yderligere ved at inkorporere hastighedsbegrænsende membraner eller polymermatricer for at kontrollere frigivelsen af ​​hvert lag uafhængigt.

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