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In che modo condizioni della pelle come l'acne o l'eczema possono influenzare l'assorbimento dei cannabinoidi dai cerotti transdermici?

In che modo condizioni della pelle come l'acne o l'eczema possono influenzare l'assorbimento dei cannabinoidi dai cerotti transdermici? Condizioni della pelle come l'acne o l'eczema possono alterare la permeabilità della pelle, aumentando potenzialmente l'assorbimento dei cannabinoidi a causa di infiammazioni o di una funzione barriera interrotta. Al contrario, la pelle danneggiata può anche portare ad un assorbimento o irritazione incoerente. Aggiustamenti della formulazione, come l'utilizzo di adesivi più delicati o composti idratanti, possono migliorare le prestazioni del cerotto sulla pelle compromessa. Clinicamente, queste condizioni possono richiedere formulazioni di cerotti su misura per effetti terapeutici ottimali (Baswan et al., 2020).

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