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Hoe beïnvloeden CBD en THC het proces van neurogenese in de hippocampus bij patiënten met depressie of PTSS? CBD en THC bevorderen de neurogenese door CB1- en CB2-receptoren te activeren en neuro-ontstekingen in de hippocampus te verminderen. THC stimuleert direct de endocannabinoïdesignalering, waardoor de groei van nieuwe neuronen wordt bevorderd, terwijl CBD dit proces ondersteunt door oxidatieve stress te verminderen en de activiteit van de serotoninereceptor te verhogen. Samen verbeteren ze de stemmingsregulatie en cognitieve functie bij patiënten met depressie en PTSS. Deze synergie herstelt de plasticiteit van de hippocampus en vermindert symptomen zoals angst en emotionele ontregeling. De gecombineerde effecten zorgen voor een holistische benadering van de behandeling in de geestelijke gezondheidszorg.
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