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Kako CBD i THC moduliraju upalni odgovor kod pacijenata s astmom i kakav to učinak ima na funkciju pluća?

Kako CBD i THC moduliraju upalni odgovor kod pacijenata s astmom i kakav to učinak ima na funkciju pluća? CBD i THC smanjuju upalu dišnih putova interakcijom s CB2 receptorima na imunološkim stanicama, smanjujući proizvodnju proupalnih citokina. Antioksidativna svojstva CBD-a ublažavaju oksidativni stres u plućima, dok bronhodilatacijski učinci THC-a poboljšavaju protok zraka. Zajedno smanjuju simptome astme i sprječavaju dugotrajna oštećenja pluća uzrokovana kroničnom upalom. Njihova kombinirana protuupalna i bronhodilatacijska svojstva poboljšavaju funkciju pluća i učinkovitost disanja. Ovi učinci nude komplementaran pristup liječenju astme bez oslanjanja isključivo na tradicionalne lijekove.
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