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Kako CBD modulira THC-induciranu disregulaciju hipotalamičkih signalnih putova?

Kako CBD modulira THC-induciranu disregulaciju hipotalamičkih signalnih putova? CBD može modulirati THC-induciranu disregulaciju hipotalamičkih signalnih putova djelujući na receptore i signalne molekule koje pomažu regulirati reakcije na stres, metabolizam i lučenje hormona. THC može poremetiti osovinu hipotalamus-hipofiza-nadbubrežna žlijezda (HPA), što dovodi do neravnoteže u kortizolu i drugim hormonima povezanim sa stresom. CBD, kroz svoju interakciju s CB1 i CB2 receptorima, može pomoći vratiti normalnu funkciju HPA osi, smanjujući prekomjernu stimulaciju uzrokovanu THC-om. Dodatno, protuupalni i neuroprotektivni učinci CBD-a mogu dodatno ublažiti utjecaj THC-a na signaliziranje hipotalamusa. Ova interakcija sugerira da bi se CBD mogao koristiti za smanjenje poremećaja hormonalne regulacije izazvanih THC-om i poboljšanje ukupne homeostaze.

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